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Amylin receptors are considered proven drug targets and amylin mimetics are emerging as novel treatments for overweight, obesity and diabetes mellitus

A key consideration is blood thickening, which can have implications for cardiovascular health

Comorbidities: Patients who have two or more comorbidities (like diabetes and heart disease) have a greater chance of being overweight

The autoimmune mechanism is a key linking pathway specifically in the association between T1DM and epilepsy: glutamic acid decarboxylase antibodies play a central role in this connection, and translocator protein, a differentially expressed gene upregulated in both, may also be involved in this regulatory process (92)